Rapamune

1-Active Ingredient:
Sirolimus

2-Concentration:
-oral solution contains 1 mg/ 1 ml Sirolimus
-tablet contains 1 mg or 2 mg Sirolimus

3-Dosage form:
-oral solution
-tablets

4-Indication:
For the prophylaxis of organ rejection in patients aged 13 years or older receiving renal transplants

5-Side effect:
-immunosuppresion
-increased susceptibility to infection and the possible development of lymphoma and the other malignancies, particularly of the skin
-over suppression of the immune system can also increase susceptibility to infection including opportunistic infection
-fatal infection
-sepsis
-deterioration of renal function (with long term admenstration)

6-Contraindication:
It’s contraindicated in patients with hypersensitivity to Sirolimus or its derivatives or any component of the drug product

7-Precautions:
*general
-its intended only for oral administration
-lumphocele occurred significantly more often in a dose related fashion in patients treated with rapamune so appropriate operative measures should be considered to minimize this application
*lipids
-rapamune use in renal transplant patients was associated with increased serum cholesterol and triglycerides that may require treatment
*renal function
Patients treated with cyclosporine and rapamune were noted to have higher erum creatinine levels and lower glomerular filtration rates compared with patients treated with cyclosporine and placebo or azathioprine controls.
*calcineurin inhibitor- induced hemolytic uremic syndrome
The concomitant use of Sirolimus with a calcineurin inhibitor may increase the risk of calcineurin inhibitor- induced HUS/TTP/TMA
*concomitant use of angiotensin- converting enzyme (ACE) inhibitors
In rare cases the concomitant administration of Sirolimus and ACE inhibitors has resulted in angioneurotic edema type reaction
*antimicrobial prophylaxis
-cases of pneumocystis crainii pneumonia have been reported in patients not receiving antimicrobial prophylaxis so it should be administered for a year after transplantation
-cytomegalovirus prophylaxis is recommended for 3 months after transplantation
*intestinal lung disease
Cases of intestinal lung disease, some fetal , with no identified infectious etiology have occurred in patients receiving immunosuppressive regimen sometimes it has resolved by discontinuation or dose reduction. The risk increase by increasing concentration
*pregnancy
- Sirolimus was embryo/feto toxic in rates at dosage of 0.1 mg/ kg
-embryo/feto toxicity was manifested as mortality and reduced fetal weight
*lactation
- Sirolimus is excreted in trace amounts in milk of lacting rats, it’s not known whether its excreted in human milk or not
-the safety profiles of Sirolimus in infants are not known
*pediatric use
-the safety and efficacy of rapamune in pediatric patients below the age of 13 years have not been established
*geriatric use
-clinical studies of rapamune oral solution or tablet didn’t include sufficient numbers of patients aged 65 years or over to determine whether safety and efficacy differ in this population from younger people.

8-Dose:
It is recommended that rapamune oral solution and tablets be used initially in regimen with cyclosporine and corticosteroid for 2 to 4 months after transplantation in patients at low to moderate immunological risk

9-Over dose:
General supportive measures should be followed in all cases of overdose based on the poor aquoues solubility and the high erythrocyte and plasma protein binding of Sirolimus, it is anticipated that Sirolimus is not dialyzable to any extent. in mice and rats the acute oral lethal dose was greater than 800 mg/kg

10-Storage:
*oral solution:
-should be protected from light
-Refrigerated at 2 – 4 C
-once the bottle opened the continents should be used within one month
*tablets:
-should be stored at 20-25 C-use cartons to protect blister cards and strips from light
-dispense in a tight light resistant containers

11-Package:
Tablets: box containing 10 strips each contain 10 tablets

12-produced by:
Wyeth pharmaceuticals

13-Price:
-oral solution: 169 £
-tablets: 90 £

Amoxil

1-Active Ingredient:
-amoxicillin

2-Concentration:
-Injections 250 mg – 500 mg – 1 g amoxicillin
-Capsules 250 mg – 500 mg amoxicillin
-syrup 125 mg amoxicillin
-syrup forte 250 mg amoxicillin
-pediatric drops 125 mg amoxicillin

3-Dosage form:
-Injections
-Capsules
-syrup
-syrup forte
-pediatric drops

4-Indication:
-respiratory tract infection
-ear, nose and throat infection
-urinary tract infection
-Gastro-intestinal infection
-enteric fever
-skin and soft tissue infection
-Biliary tract infection
-orthopedic infection
-pelvic infection
-gonorrhea
-syphilis
-septicemia
-endocarditis
-meningitis
-peritonitis
-dental abscess

5-Side effect:
-diarrhoea
-indigestion
-occasional rash
- erythematous rash

6-Contraindication:
It should not be administered in patients hypersensitive to penicillin


7-Precautions:
-during treatment with high doses an adequate fluid intake and urinary output must be maintained
-indwelling urinary catheters should be regularly checked for potency since high urinary concentration of some drug may precipitate out of solution

8-Dose:
*general recommendation:
Adult:
-oral / IM injection: 250 – 500 mg every 8 hours
-IV injection / infusion: 500 mg – 1 g every 4 – 6 hours
Children:
- Oral / IM injection: 125 mg three times daily increasing to 250 mg in severe infection.
Amoxil pediatric drops are recommended for children under 6 months: 35 – 100 mg/kg/day.
-IV injection / infusion: up to 100mg/ kg / day in divided doses every 6 hours by infusion over 30 minutes
*specific dosage recommendation:
-Typhoid and Paratyphoid:
Adults…….. 4 gm daily for 14 – 21 days
Children………100 mg / kg / day in divided doses for 14 – 21 days
-Typhoid carrier states …… 3 – 4 gm daily for a minimum of one month
-gonorrhea ……….. Single dose of 3 gm plus 1 gm probenecid
-uncomplicated urinary tract infection……… a single dose of 3 gm
-meningitis:
Adult ……. 150 mg / kg / day in equally divided doses
Children …..100 – 150 mg / kg / day in equally divided doses
-syphilis …….. 250 mg every 6 hours for 4 weeks up to 5 months
-sever or recurrent lower respiratory tract infection ……. 3 gm twice daily
-dental abscess …….. Two 3 gm doses with 8 hours between doses
-otitis media …… 750 mg twice a day used in children from 3 – 10 years

9-Over dose:
-Since it is a penicillin over dose problems are unlikely to be encountered
-Will produce very high urinary concentration
-Crystalluria is possible
- The antibiotic is removed by heamodialysis

10-Storage:
-store in dry place below 25 C
-once dispensed the syrups should be used in 7 days
-keep out of reach of children

11-Package:
-injection: vials containing 250 mg or 500 mg or 1 g amoxicillin
-capsules: box of 12 capsules
-syrup: bottle of 60 ml of 250 mg or 125 mg

12-produced by:
Beecham pharmaceuticals

13-Price:
-amoxil 500 capsules……. 7.00 L.E
-amoxil 250 suspension……5.50 L.E
-amoxil 125 suspension…….3.75 L.E
-amoxil 500 vial ……4.50 L.E
-amoxil 250 vial……..3.20 L.E

Tenolat SR

1-Active Ingredient:
-Nifedipine
-Atenolol

2-Concentration:
Each capsule contains:
-Nifedipine 20 mg
-Atenolol 50 mg

3-Dosage form:
-Capsules

4-Indication:
-All forms of hypertension including renal hypertension
-Angina (prinze metal’s angina, chronic stable angina)

5-Side effect:
-Gastrointestinal troubles
-Headache
-Tachycardia
-dizziness
-Fatigue
-Flushing
-Hypotension
-Peripheral oedema
-Hyperdiasis.

6-Contraindication:
-Sensitivity to Nifedipine and Atenolol
-Acute myocardial infraction
-Chronic obstructive airway disease


7-Precautions:
These may need control adjustment:
-Pregnancy
-Diabetes mellitus
-Acute heart failure

8-Dose:
-Hypertension: 1 capsule once daily
-Angina: 1 capsule twice daily
Or as prescribed



9-Over dose:
-Stomach should be emptied by aspiration and lavage
-Hypotension treated by laying the patient in supine position and feet raised
-standard measures (atropine for bradycardia – noradrenalin for hypotension)

10-Storage:
-Store at 25 C

11-Package:
-Pack of 20 capsules in 2 blisters

12-produced by:
SIGMA pharmaceutical industries

13-Price:
10 L.E

nilsid

1-Active Ingredient:
Nimesulide

2-Concentration:
-each tablet contains nimesulide 100 mg
-each 5 ml suspension contains nimesulide 50 mg
-each 100 g cream contains nimesulide 5 g

3-Dosage form:
-tablet
-suspension
-cream

4-Indication:
-painful inflammatory condition
-osteoarthritis
-rheumatoid arthritis
-ankylosing spondylitis
-acute gout
-painful musculoskeletal conditions
-toothache and after orodental surgery
-primary dysmenorrheal and other gynecological disorders
-conditions associated with fever

5-Side effect:
-mild gastrointestinal disturbances
-skin rashes (rarely)

6-Contraindication:
-hypersensitivity to nimesulide
-active peptic ulcer
-sever hepatic or renal impairment
-pregnancy

7-Precautions:
It should be used with cautious in patients with history of
-peptic ulcer
-ulcerative colitis
-crhon’s disease

8-Dose:
-Tablets and suspension:
Adults: one tablet or 10 ml suspension twice daily or as prescribed


Children: ½ - 1 teaspoonful twice daily or as prescribed
-Cream: apply sufficient amount of the cream to the affected area of the skin with gentel rubbing 3 – 4 times daily

9-Over dose:
………………….

10-Storage:
-keep at a temperature (15 – 30 C)
-keep out if reach of children

11-Package:
-tablets: box containing 10 or 20 tablets
-suspension: bottle containing 120 ml suspension
-cream: tube containing 20 g cream

12-produced by:
Pharaonia Pharmaceuticals

13-Price:
-tablet: 9.00 L.E
-suspension: 6.00 L.E
-cream: 4.50 L.E

neurovit

1-Active Ingredient:
-thiamine HCL (vitamin B1)
-pyridoxine HCL (vitamin B6)
-cyanocobalamine (vitamin B12)
2-Concentration:
-thiamine HCL (vitamin B1) …………. 250 mg
-pyridoxine HCL (vitamin B6)…………100 mg
-cyanocobalamine (vitamin B12)……….250 mcg
3-Dosage form:
Sugar coated tablets

4-Indication:
-metabolic disorder
-anemia
-peripheral neuritis
-demyelination and other neurological disorders
-chronic and acute beri-beri
-Improvement of fat - carbohydrate – amino acid metabolism
-depletion or increased demands of vitamin B1 , B6 or B12

5-Side effect:
……………………

6-Contraindication:
Not known

7-Precautions:
………………….

8-Dose:
1 – 3 tablets daily or as prescribed

9-Over dose:
………………

10-Storage:
-store at 25 C

11-Package:
A box containing 2 strips 10 tablets each

12-produced by:
European Egyptian pharmaceuticals

13-Price:
6.00 L.E

NATRILIX - SR

1-Active Ingredient:
-Indapamide

2-Concentration:
-Each tablet contains 1.5 mg indapamide

3-Dosage form:
-Sustained release tablets

4-Indication:
-Essential hypertension

5-Side effect:
-Fatigue
-Allergic manifestation
-Skin rash
-Feeling of vertigo when changing from lying to standing position
-Dehydration (elderly)
-Heart failure (elderly)
-Variation in blood parameters

6-Contraindication:
This drug must not be taken when:
-Known allergy to this drug or to sulphonadmides.
-Renal failure.
-Serious liver disease.
-Hypokalemia.

7-Precautions:
*Use cautiously when:
-Having disturbed water/ electrolyte balance
-diabetes
-gout
-kidney problems
*Pregnancy and lactation:
-Inform your physician if you are pregnant, breast feeding or trying to get pregnant.
*Drivers and machinery operators:
-Decrease in blood Pressure may occur so the ability to drive or use machines may be diminished.
*Athletes:
- It may induce a positive reaction during antidoping testes.

8-Dose:
One tablet per day preferably at morning

9-Over dose:
-Doctor must be consulted immediately
-Signs of acute poisoning in the form of water/ electrolyte disturbance
-Measures involve rapid elimination of the ingested substances by gastric wash-out or administration of activated charcoal followed be restoration of water/ electrolyte balance

10-Storage:
-Do not exceed the expiry date
-Should be protected from humidity
-Store at room temperature (15 – 25 C)
-Keep out of reach of children

11-Package:
-Box of 30 coated tablets

12-produced by:
Servier Egypt Industries Limited

13-Price:
11 L.E

callocure

1-Active Ingredient:
-Salicylic acid
-Lactic acid
-Flexible collodion

2-Concentration:
Per 10 gm
-Salicylic acid 1 gm
-Lactic acid 1.5 gm
-Flexible collodion 6.9 gm

3-Dosage form:
-Solution

4-Indication:
-For the removal of corns, warts weals and callus

5-Side effect:
………………..

6-Contraindication:
………………….

7-Precautions:
…………………..

8-Dose:
-Callus: twice a day directly on callus
-Corns: twice a day directly on corns
-Warts: twice a day directly on small to medium size warts

9-Over dose:
………………..

10-Storage:
-Store carefully
-Keep out of reach of children
-Close the bottle immediately after use

11-Package:
Bottle containing 10 ml with an easily use applicator

12-produced by:
Mash company for pharmaceutical industries

13-Price:
5.00 L.E

Buscopan plus

1-Active Ingredient:
-hyoscine-N-butylbromide
-Paracetamol


2-Concentration:
*film coated tablets:
-hyoscine-N-butylbromide 10 mg
-Paracetamol 500 mg
*suppositories
-hyoscine-N-butylbromide 10 mg
-Paracetamol 800 mg

3-Dosage form:
-tablets
-suppositories

4-Indication:
-paroxysmal pain in stomach or intestine diseases
-spastic pain
-functional disorder in biliary and urinary tracts and female genital organs

5-Side effect:
-allergic reaction with exanthema
-allergic platelet deficiency
-reduction in leucocytes
-reduction in granulocytes
-reduction in cellular blood elements
-spasms in the bronchial muscles in cases of bronchial asthma


6-Contraindication:
It should not be used when:
-known genetically determined glucose-6-phosphate dehydrogenase deficiency
-known hypersensitivity to paracetamol

7-Precautions:
It should be used with cautious in:
-hepatic dysfunction
-renal dysfunction
-Gilbert’s syndrome
*pregnancy and lactation:
-Available but limited preclinical data had shown no hazard but safety on human pregnancy and lactation has not been established yet

8-Dose:
*tablets:
-1 – 2 tablets three times daily
-the total daily dose should not exceed 6 tablets
*suppositories
- 1 suppository 3 to 4 times daily
-the total daily dose should not exceed 4 suppositories
* the tablets and suppositories are not suitable for children

9-Over dose:
*symptoms:
In case of sever paracetamol poisoning:
-circulatory collapse
-acute renal insufficiency
-icterus and hepatic coma
In case of chronic intoxication:
-hemolytic anemia
-cyanosis
-weakness
-dizziness
-paraesthesia
-tremor
-insomnia
-headache
-falling memory
-central nervous irritation
-delirium and convulsion
*therapy:
-the administration of the drug should be stopped immediately and medical advice sought

10-Storage:
-store at 25 C
-keep out of reach of children

11-Package:
-Film coated tablets: box of 20 tablets
-Suppositories: box of 5 suppositories

12-produced by:
-Chemical industries development

13-Price:
3.65 L.E

betacor

1-Active Ingredient:
-Stalol HCL

2-Concentration:
-Each tablet contains stalol HCL 80 mg

3-Dosage form:
-Tablet

4-Indication:
-Sustained ventricular tachycardia.
-Ventricular tachyarrythmias.
-Paroxysmal supraventricular tachycardia.
-Wolff-Parkinson white syndrome.
-Recurrence of atrial fibrillation.
-Angina pectoris and essential hypertension.

5-Side effect:
-Hypotension
-Bradycardia
-Conduction disturbances in AV node

6-Contraindication:
-Artioventricular block.
-Heart failure.
-Bronchial asthma.
-Diabetic ketoacidosis
-Metabolic acidosis
-Pregnancy and lactation
-Hypersensitivity to the drug

7-Precautions:
……………..

8-Dose:
-160 mg once daily or 80 gm twice daily.
- It may be increased up to 480 mg / day for emergency treatment of cardiac arrhythmias

9-Over dose:
…………………..

10-Storage:
-Keep out of reach of children.
-store at 25 C

11-Package:
-strips of 10 tablets in packs of 1 strip or 3 strips

12-produced by:
-AMOUN Pharmaceutical company

13-Price:
4.00 L.E

Asylon

1-Active Ingredient:
-Calcium carbonate
-Glycine
-Dimethicone

2-Concentration:
Each tablet contains:
-Calcium carbonate 420 mg
-Glycine 180 mg
-Dimethicone 135 mg

3-Dosage form:
-Chewable tablets

4-Indication:
-All forms of hyperacidity
-Dietary or drug or alcohol induced gastritis
-Heart burn in pregnancy
-Symptomatic relief in peptic ulceration
-Dyspepsia, flatulence, abdominal distension and meteorism

5-Side effect:
-Constipation
-Hypocalcaemia
-Milk-alkali
-May interfere with absorption of concomitantly administered tetracycline preparations

6-Contraindication:
-Hypocalcaemia
-Hyperparathyroidism
-Hypercaciuria
-Nephrolithiasis
-Concomitant digoxin therapy

7-Precautions:
…………………….

8-Dose:
-One or two tablets to be chewed after or between meals and repeated when needed every 4-6 hours

9-Over dose:
…………………..


10-Storage:
-Store below 25 C


11-Package:
-Strips, each strip contain 10 tablets

12-produced by:
Chemipharm pharmaceutical industries

13-Price:

Antiflam

1-Active Ingredient:
-Declofenac potassium

2-Concentration:
-Declofenac potassium 25 mg or 50 mg

3-Dosage form:
-film coated tablets

4-Indication:
It is effective analgesic anti-inflammatory drug which used in:
-postoperative pain
-inflammation and swelling
-post-traumatic pain
-non-articular rheumatism
-painful conditions related to vertebral column and muscles
-painful gynecological inflammation
-painful conditions in the ear nose and sinusitis and throat

5-Side effect:
*gastrointestinal tract:
-epigastric pain
-nausea
-vomiting
-diarrhea
-abdominal cramps
-dyspepsia
-flatulence
-anorexia
-gastrointestinal bleeding
-gastric or intestinal ulcer
*central nervous system:
-headache
-dizziness
-sedation
*skin:
-transient urticariea

6-Contraindication:
-treatment must stop if any allergic reaction occurs

7-Precautions:
*It should be administered with caution in patients with:
-active peptic ulcer
-ulcerative colitis
-crohn’s disease
-impaired hepatic or renal function
-cardiac dysfunction
-significant loss of body fluids
*pregnancy:
It should be employed only for compelling reasons and in the lowest effective dose
*breast feeding:
It passes into breast milk but in amounts that are too small to produce undesirable effects
*driving and using machines
Not studied

8-Dose:
*Adults and children over 12 years:
-The recommended daily dosage is 100 – 150 mg divided into 3 or 4 doses
-In milder cases age 75 – 100 mg is usually sufficient
*infants and children up to 12 years:
-tablets are not recommended for use in children

9-Over dose:
There is no typical clinical picture associated with over dose of diclofenac

10-Storage:
-Store between 15 – 30 C
-protect from moisture and light
-keep out of reach of children
-do not use after the expiry date

11-Package:
-strips of 10 tablets in packs of 1 strip

12-produced by:
T3A industerial

13-Price:
-Antiflam 25 3.35 L.E
-Antiflam50 5.35 L.E

PROTELOS 2g

1-Active Ingredient:
-Strontium ranelate
-excipients q.s. for one sachet
-aspartame (E 951)

2-Concentration:
- Strontium ranelate: 2 gm

3-Dosage form:
-Granules for oral suspension

4-Indication:
-Non hormonal medicine used to treat osteoporosis in postmenopausal women
-Reduces the risk of fracture at the spine and hip

5-Side effect:
-Nausea
-Diarrhea
-Headache
-Skin irritation
-Blood clots
-Fainting fit
-Memory troubles
-Seizures (rarely)

6-Contraindication:
-Do not take this medicine if you are hypertensive to Strontium ranelate or any of the other ingredients

7-Precautions:
-Take special care with protelos:
*If you have severe kidney disease
*if you are being treated or have been treated for blood clots
*if you are confined to bed
*if you are to undergo an operation
-It’s not intended for use in children and adolescent.
-Taking with food and drink:
*food, milk and milk products reduce the absorption of Strontium ranelate
*its recommended to be taken between meals, preferably at bed time at least two hours after food, milk or milk products and calcium supplement.
-Pregnancy and breast feeding:
*It’s meant only for postmenopausal women.
* Should not be taken during pregnancy or breast feeding.
* If taken by accident stop taking it straight way and talk to your doctor.
-Driving and using machines:
*Not known to affect ability of driving or using machines


8-Dose:
-The recommended dose is one 2 gm sachet per day at bed time and you may lie down immediately after taking it if you wish


9-Over dose:
-If you take too many sachets tell the doctor or pharmacist they may advise taking milk or antacid to reduce absorption of active ingredient.
-If you forgot a dose don’t double the next one to make it up just carry on with the next one at normal time

10-Storage:
-Keep out of reach and sight of children
-Do not use after the expiry date indicated on the box and sachet
-Store below 30 C

11-Package:
Box of 14 sachets

12-produced by:
Servier Egypt Industries Limited

13-Price:
124 L.E

duphalac

1-Active Ingredient:
-Lactulose
-Galactose
-Lactose

2-Concentration:
Lactulose 667 gm/ L

3-Dosage form:
Syrup

4-Indication:
-Constipation
-Portal systemic encephalopathy (P.S.E)
-samonellosis

5-Side effect:
-No serious side effects
-Flatulence (disappears spontaneously or with adjustment of dose)

6-Contraindication:
No contraindications are known

7-Precautions:
-The syrup contains small amounts of galactose and lactose this should be taken in consideration when treating diabetic patients and patients on galactose-free diet.
-the dosage in the treatment of pre comma hepaticum is usually much higher and may pose a problem for diabetics.

8-Dose:
-Constipation:
*It varies according to the individual response
*starting dose:
Adults: 15 - 45 ml per day
Children 7 - 14 years: 15 ml per day
Children 1 - 6 years: 5 - 10 ml per day
Infants: 5 ml per day
*Maintenance dose:
Adults: 10 - 25 ml per day
Children 7 – 14 years: 10 ml per day
Children 1 – 6 years: 5 – 10 ml per day
Infants: 5 ml per day

-Portal systemic encephalopathy (P.S.E)
*starting dose: 30 – 35 ml three times daily
* Maintenance dose has to be adjusted to the individual response

-samonellosis
*First cycle of treatment (10 – 12 days): 15 ml three times daily.
*Second cycle of treatment (10 – 12 days): after a non treatment period of 7 days 15 ml five times daily.
*Third cycle of treatment if necessary: after having 7 days without treatment should be 30 ml three times daily.

-Duphalac may if necessary be diluted with water or fruit juice, etc.


9-Over dose:
…………….

10-Storage:
Store at 25 C

11-Package:
Bottles of 120 or 300 ml

12-produced by:
Pharco Pharmaceutics

13-Price:
5.90 L.E

DOMPIDONE

1-Active Ingredient:
Domperidone

2-Concentration:
*Tablet: Domperidone 10 mg / tablet
* Oral suspension: 1 mg / 1 ml
* Suppositories: 60 mg / supp. For adult
30 mg / supp. For children
10 mg / supp. For babies

3-Dosage form:
*Tablets
* Oral suspension
* Suppositories

4-Indication:
*Acute nausea and vomiting caused by levodopa or bromocriptin administration in Parkinson’s disease.
*Gastro-esophageal reflux.
*Irritable bowel syndrome.

5-Side effect:
*it has been well tolerated in most patients
*neurological side effects
*dry mouth
*transient skin rash or itching
*headache
*thirst
*diarrhea
*very mild nervousness
*Dystonic reactions (rarely in adult and children)


6-Contraindication:
…………….

7-Precautions:
*should not be used whenever gastric motility might be dangerous e.g. (gastrointestinal hemorrhage – mechanical obstruction or perforation)
*It should not be used in patients with hepatic or renal impairment (specialy oral suspension as it contains propylene glycol)
*it should be used for 12 weeks only in patients with Parkinson’s disease
*it can cross the blood-brain barrier so there is risk of central effects so it should only be used in pakinsonian patients when safer anti-emetic measures have failed.

8-Dose:

*Tablets:
-For acute nausea and vomiting: 10 to 20 mg three times daily
-For reflux oesophagitis: 20 mg four times daily
-For reflux chronic gastritis: 30 mg four times daily
-For irritable bowel syndrome: 10 mg three times daily
-For patients with chronic postprandial dyspepsia: 10 mg three times daily 15 to 30 minutes before meals and at bed time if nessacary
- For peptic ulcer treatment: 20 mg three times daily before meals

*Oral suspension for children:
-chronic dyspepsia: 2.5 ml per 10 kg body weight three times daily before meals and one more at the evening if necessary ( if results are not satisfactory he dose should be doubled in children over two years of age )
-nausea and vomiting: 5 ml per 10 kg body weight three times daily before meals and before bed time

*rectal suppositories:
-Adult: 2 to 4 suppositories “adult” (60 mg) per day
-Over 2 years: 2 to 4 suppositories “children” (30 mg) per day
-Up to 2 years: 2 to 4 suppositories “babies” (10 mg) per day

9-Over dose:
…………….

10-Storage:
Store at 25 C

11-Package:
*Oral suspension: glass bottles of 100 ml & 200 ml
*Tablets: box of 30 tablets in strip
*Suppositories:
-Adult: box of 6 suppositories (60 mg / supp.)
-Children: box of 6 suppositories ( 30 mg / supp.)
- Babies: box of 6 suppositories (10 mg / supp.)

12-produced by:
The arab drug company

13-Price:
*Tablet: 6.60 L.E
*Suspension: 4.00 L.E
*suppositories:
-Adult: 9.00 L.
-Children: 5.00 L.E
-Babies: 2.50 L.E

SEDO - MAG

1-Active Ingredient:
-Magaldrate
-Simethicone
-Soudim alginate

2-Concentration:
-Each teaspoonful (5 ml) contains: Magaldrate 480 mg
Simethicone 100 mg
Soudim alginate 50 mg

3-Dosage form:
-Suspension

4-Indication:
-Upset stomach associated with hurt burn
- sour stomach and / or acid indigestion
-Hyperacidity associated with peptic ulcer
-gastritis
- peptic oesophagitis and hiatal hernia
-Gastro-oesophsgeal reflex
-Flatulence and meteorism
-Elimination of gas air or foam from GIT before radiography
-Posteopertive gas pain , endoscopic examination


5-Side effect:
-There is no side effects

6-Contraindication:
-Hypersensitivity of any of the ingredients

7-Precautions:
-Patients with kidney failure should not use this product
-Antacids may mask the symptoms of the internal bleeding secondary to the nonstroidal anti- inflammatory drugs
-Avoid use of antacids with these drugs ( Tetracycline – Quinolones – Propranolol – Ranitidine – Atenolol – Famotidine & Asprin)

8-Dose:
-One or two teaspoonful between meals and at bed time.
Note: shake the bottle well before use.

9-Over dose:
…………….


10-Storage:
-Keep at temperature not exceeding 30̊ C
-Keep the medicine out of reach of children

11-Package:
-Bottle of 120 ml

12-produced by:
SEDICO pharmaceutical company

13-Price:
4.00 L.E

Acicone - S

1-Active Ingredient:
- Magaldrate
- Simethicone

2-Concentration:
- Tablet : Magaldrate 720 mg
simethicone 25 mg
- Each 5 ml suspension : Magaldrate 540 mg
simethicone 40 mg

3-Dosage form:
- Tablet
- Suspension

4-Indication:
- Heart burn
- Sour stomach
- Acid indigestion
- Hyperacidity with peptic ulcer
- Gastritis
- Reflex oesophagitis
- Hiatus hernia
- Prophylactic against ulcer complications

5-Side effect:
- Mild diarrhea (or constipation)
- Nausea
- Vomiting
- Abdominal cramps (rarely)

6-Contraindication:
…………

7-Precautions:
- Individuals with renal failure should not take this product
- Not to be taken with tetracycline antibiotic
- Not to be taken for long time unless directed by physician

8-Dose:
- Tablets : one tablet to be chewed thoroughly or sucked , on the first appearance of the symptoms or 30 minutes to one hour after meals and at bed time or as directed
- Suspension : 1-2 teaspoonful on the first appearance of the symptoms or 30 minutes to one hour after meals and at bed time or as directed


9-Over dose:
……………..

10-Storage:
- Store at 25 ̊ C

11-Package:
-Tablet: Box containing 20 chewable tablets.
Box containing 30 strips (each strip contains 4 chewable tablets )

-Suspension : Bottle containing 200 ml suspension
Bottle containing 120 ml suspension

12-produced by:
Medical union pharmaceutics

13-Price:
- Tablet : 4.50 L.E
- Suspension : 6.00 L.E